In utero exposure to cigarette smoke and effects across generations: A conference of animals on asthma.
The prevalence of asthma and chronic obstructive pulmonary disease (COPD) has risen markedly over the last decades and is reaching epidemic proportions. Of note, recent evidence suggests that the disease risk can be transferred across generations, that is, from grandparents to their grandchildren. This review summarizes current knowledge on this topic derived from mouse models, while also introducing two other relevant animal models: the fruit fly Drosophila melanogaster and the zebrafish Danio rerio. Read the full text here