Papers and abstracts

Publications

Published papers and abstracts from ongoing research within RHINESSA and other closely related publications by the RHINESSA group.

Papers

Gyawali S, López-Cervantes JP, Johannessen A, Gislason T, Holm M, Janson C,
Jögi R, Modig L, Schlünssen V, Mustafa T, Svanes C. Maternal and paternal
tuberculosis is associated with increased asthma and respiratory symptoms in
their offspring: a study from Northern Europe. Front Allergy. 2023 Jun
8;4:1193141. doi: 10.3389/falgy.2023.1193141. PMID: 37361110; PMCID:

Shigdel R, Johannessen A, Lin H, Peddada S, Gómez Real F, Ringel-Kulka T,
Svanes C, Bertelsen RJ. Oral bacterial composition associated with lung function
and lung inflammation in a community-based Norwegian population. Respir Res.
2023 Jul 12;24(1):183. doi: 10.1186/s12931-023-02491-6. PMID: 37438766; PMCID:

Khomich M, Lin H, Malinovschi A, Brix S, Cestelli L, Peddada S, Johannessen
A, Eriksen C, Real FG, Svanes C, Bertelsen RJ. Association between lipid-A-
producing oral bacteria of different potency and fractional exhaled nitric oxide
in a Norwegian population-based adult cohort. J Transl Med. 2023 May
29;21(1):354. doi: 10.1186/s12967-023-04199-z. PMID: 37246224; PMCID:

Kisiel MA, Sedvall M, Malinovschi A, Franklin KA, Gislason T, Shlunssen V,
Johansson A, Modig L, Jogi R, Holm M, Svanes C, Lindholdt L, Carlson M, Janson
C. Inflammatory bowel disease and asthma. Results from the RHINE study. Respir
Med. 2023 Sep;216:107307. doi: 10.1016/j.rmed.2023.107307. Epub 2023 Jun 2.

Svanes C, Holloway JW, Krauss-Etschmann S. Preconception origins of asthma,
allergies and lung function: The influence of previous generations on the
respiratory health of our children. J Intern Med. 2023 May;293(5):531-549. doi:
10.1111/joim.13611. Epub 2023 Mar 1. PMID: 36861185. Read the full text here​

Savouré M, Eminson K, Sese L, Dumas O, Cai YS. The exposome in respiratory
diseases: multiple preventable risk factors from early life to adulthood.
Breathe (Sheff). 2023 Jun;19(2):230034. doi: 10.1183/20734735.0034-2023. Epub
2023 Jun 13. PMID: 37377849; PMCID: PMC10292782. Read the full text here​

Vindenes HK, Bertelsen RJ, Lygre SHL, Morken T, Møllerløkken OJ, Irgens-
Hansen K. Changes in Infection Prevention Practices and Occurrence of Skin
Symptoms among Healthcare Workers, Cleaners and Day-care Workers in Norway
during the COVID-19 Pandemic. Acta Derm Venereol. 2023 Jan 4;103:adv00840. doi:
10.2340/actadv.v103.3420. PMID: 36600529; PMCID: PMC9885284. Read the full text here​

​Lønnebotn M, Calciano L, Johannessen A, Jarvis DL, Abramson MJ,
Benediktsdóttir B, Bråbäck L, Franklin KA, Godoy R, Holm M, Janson C, Jõgi NO,
Kirkeleit J, Malinovschi A, Pereira-Vega A, Schlünssen V, Dharmage SC, Accordini
S, Gómez Real F, Svanes C. Parental Prepuberty Overweight and Offspring Lung
Function. Nutrients. 2022 Apr 4;14(7):1506. doi: 10.3390/nu14071506. PMID:
35406119; PMCID: PMC9002985. Read the full text here

Wang J, Janson C, Malinovschi A, Holm M, Franklin KA, Modig L, Johannessen A,
Schlünssen V, Gislason T, Jogi NO, Norbäck D. Asthma, allergic rhinitis and
atopic dermatitis in association with home environment - The RHINE study. Sci
Total Environ. 2022 Dec 20;853:158609. doi: 10.1016/j.scitotenv.2022.158609.
Epub 2022 Sep 8. PMID: 36089044. Read the full text here

Svanes C, Johannessen A, Bertelsen RJ, Dharmage S, Benediktsdottir B, Bråbäck
L, Gislason T, Holm M, Jõgi O, Lodge CJ, Malinovschi A, Martinez-Moratalla J,
Oudin A, Sánchez-Ramos JL, Timm S, Janson C, Real FG, Schlünssen V; RHINESSA
International Collaboration. Cohort profile: the multigeneration Respiratory
Health in Northern Europe, Spain and Australia (RHINESSA) cohort. BMJ Open. 2022
Jun 2;12(6):e059434. doi: 10.1136/bmjopen-2021-059434. PMID: 35654464; PMCID:

López-Cervantes JP, Shigdel R, Accordini S, Mustafa T, Bertelsen RJ,
Makvandi-Nejad S, Lerm M, Horsnell W, Svanes C. Parental TB associated with
offspring asthma and rhinitis. Int J Tuberc Lung Dis. 2022 Jun 1;26(6):544-549.
doi: 10.5588/ijtld.21.0603. PMID: 35650692. Read the full text here

Madsen MK, Schlünssen V, Svanes C, Johannessen A, Jõgi NO, Holm M, Janson C,
Pereira-Vega A, Lowe AJ, Franklin KA, Malinovschi A, Sigsgaard T, Abramson MJ,
Bertelsen R, Oudin A, Gislason T, Timm S. The effect of farming environment on
asthma; time dependent or universal? Eur J Epidemiol. 2022 Jul 27. doi:
10.1007/s10654-022-00893-2. Epub ahead of print. PMID: 35900634. Read the full text here

Sirocko KT, Angstmann H, Papenmeier S, Wagner C, Spohn M, Indenbirken D,
Ehrhardt B, Kovacevic D, Hammer B, Svanes C, Rabe KF, Roeder T, Uliczka K,
Krauss-Etschmann S. Early-life exposure to tobacco smoke alters airway signaling
pathways and later mortality in D. melanogaster. Environ Pollut. 2022 Sep
15;309:119696. doi: 10.1016/j.envpol.2022.119696. Epub 2022 Jun 30. PMID:

Vindenes HK, Lin H, Shigdel R, Ringel-Kulka T, Real FG, Svanes C, Peddada SD,
Bertelsen RJ. Exposure to Antibacterial Chemicals Is Associated With Altered
Composition of Oral Microbiome. Front Microbiol. 2022 Apr 28;13:790496. doi:
10.3389/fmicb.2022.790496. PMID: 35572708; PMCID: PMC9096491. Read the full text here

Bertelsen RJ, Barrionuevo AMP, Shigdel R, Lie SA, Lin H, Real FG, Ringel-
Kulka T, Åstrøm AN, Svanes C. Association of oral bacteria with oral hygiene
habits and self-reported gingival bleeding. J Clin Periodontol. 2022
Aug;49(8):768-781. doi: 10.1111/jcpe.13644. Epub 2022 Jun 10. PMID: 35569028. Read the full text here

Jõgi NO, Kitaba N, Storaas T, Schlünssen V, Triebner K, Holloway JW, Horsnell
WGC, Svanes C, Bertelsen RJ. Ascaris exposure and its association with lung
function, asthma, and DNA methylation in Northern Europe. J Allergy Clin
Immunol. 2022 Jun;149(6):1960-1969. doi: 10.1016/j.jaci.2021.11.013. Epub 2022
Jan 4. PMID: 34996616. Read the full text here

Heldin J, Malinovschi A, Johannessen A, Alving K, Holm M, Franklin KA,
Forsberg B, Schlünssen V, Jögi R, Gislason T, Benediktsdottir B, Svanes C,
Janson C. Clinical Remission of Asthma and Allergic Rhinitis - in a Longitudinal
Population Study. J Asthm​​a Allergy. 2022 Nov 4;15:1569-1578. doi:
10.2147/JAA.S378584. PMID: 36387839; PMCID: PMC9643071. Read the full text here​

Rask-Andersen A, Leander M, Sundbom F, Lampa E, Oudin A, Leynaert B, Svanes
C, Gislason T, Torén K, Janson C. Healt​h-related quality of life as associated
with asthma control, psychological status and insomnia. Ups J Med Sci. 2022 Nov
29;127. doi: 10.48101/ujms.v127.8967. PMID: 36590755; PMCID: PMC9793762. Read the full text here​

Wheatley LM, Holloway JW, Svanes C, Sears MR, Breton C, Fedulov AV, Nilsson
E, Vercelli D, Zhang H, Togias A, Arshad SH. The role of epigenetics in multi-
generational transmission of asthma: An NIAID workshop report-based narrative
review. Clin Exp Allergy. 2022 Nov;52(11):1264-1275. doi: 10.1111/cea.14223.
Epub 2022 Oct 6. PMID: 36073598; PMCID: PMC9613603. Read the full text here​

López-Cervantes JP, Lønnebotn M, Jogi NO, Calciano L, Kuiper IN, Darby MG,
Dharmage SC, Gómez-Real F, Hammer B, Bertelsen RJ, Johannessen A, Würtz AML,
Mørkve Knudsen T, Koplin J, Pape K, Skulstad SM, Timm S, Tjalvin G, Krauss-
Etschmann S, Accordini S, Schlünssen V, Kirkeleit J, Svanes C. The Exposome
Approach in Allergies and Lung Diseases: Is It Time to Define a Preconception
Exposome? Int J Environ Res Public Health. 2021 Dec 1;18(23):12684. doi:
10.3390/ijerph182312684. PMID: 34886409; PMCID: PMC8657011. Read the full text here

Ingrid Nordeide Kuiper, Cecilie Svanes, Iana Markevych, Simone Accordini, Randi J Bertelsen, Lennart Bråbäck, Jesper Heile Christensen, Bertil Forsberg, Thomas Halvorsen, Joachim Heinrich, Ole Hertel, Gerard Hoek, Mathias Holm, Kees de Hoogh, Christer Janson, Andrei Malinovschi, Alessandro Marcon, Roy Miodini Nilsen , Torben Sigsgaard, Ane Johannessen. Lifelong exposure to air pollution and greenness in relation to asthma, rhinitis and lung function in adulthood. Environ Int. 2021 Jan;146:106219. doi: 10.1016/j.envint.2020.106219. Epub 2020 Oct 27. Read the full text here

Tjalvin G, Svanes Ø, Igland J, Bertelsen RJ, Benediktsdóttir B, Dharmage S, Forsberg B, Holm M, Janson C, Jõgi NO, Johannessen A, Malinovschi A, Pape K,
Real FG, Sigsgaard T, Torén K, Vindenes HK, Zock JP, Schlünssen V, Svanes C. Maternal preconception occupational exposure to cleaning products and
disinfectants and offspring asthma. J Allergy Clin Immunol. 2021 Oct 11:S0091-6749(21)01399-3. doi: 10.1016/j.jaci.2021.08.025. Epub ahead of print.
PMID: 34674855. Read the full text here

Svanes C, Bertelsen RJ, Accordini S, Holloway JW, Júlíusson P, Boateng E, Krauss-Etchmann S, Schlünssen V, Gómez-Real F, Skulstad SM. Exposures during the
prepuberty period and future offspring's health: evidence from human cohort studies†. Biol Reprod. 2021 Sep 14;105(3):667-680. doi: 10.1093/biolre/ioab158.
PMID: 34416759; PMCID: PMC8444705.​ Read the full text here​ 

Vindenes HK, Svanes C, Lygre SHL, Real FG, Ringel-Kulka T, Bertelsen RJ. Exposure to environmental phenols and parabens, and relation to body mass index, 
eczema and respiratory outcomes in the Norwegian RHINESSA study. Environ Health. 2021 Jul 13;20(1):81. doi: 10.1186/s12940-021-00767-2. PMID: 34256787; PMCID: PMC8278607. Read the full text here 

Ekström M, Johannessen A, Abramson MJ, Benediktsdottir B, Franklin K, Gislason T, Gómez Real F, Holm M, Janson C, Jogi R, Lowe A, Malinovschi A, Martínez-Moratalla J, Oudin A, Sánchez-Ramos JL, Schlünssen V, Svanes C. Breathlessness across generations: results from the RHINESSA generation study. Thorax. 2021 Jun 14:thoraxjnl-2021-217271. doi: 10.1136/thoraxjnl-2021-217271. Epub ahead of print. PMID: 34127557. Read the text here 

Hammer B, Kadalayil L, Boateng E, Buschmann D, Rezwan FI, Wolff M, Reuter S, Bartel S, Knudsen TM, Svanes C, Holloway JW, Krauss-Etschmann S. Preconceptional smoking alters spermatozoal miRNAs of murine fathers and affects offspring's body weight. Int J Obes (Lond). 2021 Jul;45(7):1623-1627. doi: 10.1038/s41366-021-00798-2. Epub 2021 May 17. PMID: 34002034; PMCID: PMC8236406. Read the full text here​ 

Kuiper IN, Markevych I, Accordini S, Bertelsen RJ, Bråbäck L, Christensen JH, Forsberg B, Halvorsen T, Heinrich J, Hertel O, Hoek G, Holm M, de Hoogh K, Janson C, Malinovschi A, Marcon A, Sigsgaard T, Svanes C, Johannessen A. Associations of Preconception Exposure to Air Pollution and Greenness with Offspring Asthma and Hay Fever. Int J Environ Res Public Health. 2020 Aug 12;17(16):5828. doi: 10.3390/ijerph17165828. PMID: 32806543; PMCID: PMC7459891.​Read the full text here 

Timm S, Svanes C, Frydenberg M, Sigsgaard T, Holm M, Janson C, Bråbäck L, Campbell B, Kjaer Madsen M, Jõgi NO, Jõgi R, Schiöler L, Bertelsen RJ, Johannessen A, Sanchez-Ramos JL, Martinez-Moretalla J, Dratva J, Dharmage S, Schlünssen V. Does parental farm upbringing influence the risk of asthma in offspring? A three-generation study. Int J Epidemiol. 2021 Jan 23;49(6):1874-1882. doi: 10.1093/ije/dyaa091. PMID: 32747948.​ Read the text here 

Pape K, Svanes C, Sejbæk CS, Malinovschi A, Benediktsdottir B, Forsberg B, Janson C, Benke G, Tjalvin G, Sánchez-Ramos JL, Zock JP, Toren K, Bråbäck L, Holm M, Jõgi R, Bertelsen RJ, Gíslason T, Sigsgaard T, Liu X, Hougaard KS, Johannessen A, Lodge C, Dharmage SC, Schlünssen V. Parental occupational exposure pre- and post-conception and development of asthma in offspring. Int J Epidemiol. 2021 Jan 23;49(6):1856-1869. doi: 10.1093/ije/dyaa085. PMID: 32666076; PMCID: PMC7825962. Read the text here

Simone Accordini, Lucia Calciano, Ane Johannessen, Bryndis Benediktsdóttir, Randi Jacobsen Bertelsen, Lennart Bråbäck, Shyamali C Dharmage, Bertil Forsberg, Francisco Gómez Real, John W Holloway, Mathias Holm, Christer Janson, Nils O Jõgi, Rain Jõgi, Andrei Malinovschi, Alessandro Marcon, Jesús Martínez-Moratalla Rovira, José Luis Sánchez-Ramos, Vivi Schlünssen, Kjell Torén, Deborah Jarvis, Cecilie Svanes. Prenatal and prepubertal exposures to tobacco smoke in men may cause lower lung function in future offspring: a three-generation study using a causal modelling approach. Eur Respir J. 2021 Apr 1;2002791. doi: 10.1183/13993003.02791-2020. Online ahead of print. Read the full text here

Triebner K, Markevych I, Bertelsen RJ, Sved Skottvoll B, Hustad S, Forsberg
B, Franklin KA, Holm M, Lindberg E, Heinrich J, Gómez Real F, Dadvand P.
Lifelong exposure to residential greenspace and the premenstrual syndrome: A
population-based study of Northern European women. Environ Int. 2022
Jan;158:106975. doi: 10.1016/j.envint.2021.106975. Epub 2021 Nov 12. PMID:

Knudsen GTM, Dharmage S, Janson C, Abramson MJ, Benediktsdóttir B,
Malinovschi A, Skulstad SM, Bertelsen RJ, Real FG, Schlünssen V, Jõgi NO,
Sánchez-Ramos JL, Holm M, Garcia-Aymerich J, Forsberg B, Svanes C, Johannessen
A. Parents' smoking onset before conception as related to body mass index and
fat mass in adult offspring: Findings from the RHINESSA generation study. PLoS
One. 2020 Jul 6;15(7):e0235632. doi: 10.1371/journal.pone.0235632. PMID:
32628720; PMCID: PMC7337347.

Jõgi NO, Kleppe Olsen R, Svanes C, Gislason D, Gislason T, Schlünssen V, Sigsgaard T, Sundbom F, Storaas T, Bertelsen RJ. Prevalence of allergic sensitization to storage mites in Northern Europe. Clin Exp Allergy. 2020 Mar;50(3):372-382. doi: 10.1111/cea.13536. [Epub ahead of print]. Read the full text here

Johannessen A, Lønnebotn M, Calciano L, Benediktsdóttir B, Bertelsen RJ, Bråbäck L, Dharmage S, Franklin KA, Gislason T, Holm M, Janson C, Jarvis D, Jõgi R, Kim JL, Kirkeleit J, Lodge C, Malinovschi A, Martinez-Moratalla J, Nilsen RM, Pereira-Vega A, Real FG, Schlünssen V, Accordini S, Svanes C. Being overweight in childhood, puberty, or early adulthood: Changing asthma risk in the next generation? J Allergy Clin Immunol. 2020 Mar;145(3):791-799.e4. doi:10.1016/j.jaci.2019.08.030. [Epub ahead of print]. Read the full text here

Accordini S, Calciano L, Marcon A, Pesce G, Antó JM, Beckmeyer-Borowko AB, Carsin AE, Corsico AG, Imboden M, Janson C, Keidel D, Locatelli F, Svanes C, Burney PGJ, Jarvis D, Probst-Hensch NM, Minelli C. Incidence trends of airflow obstruction among European adults without asthma: a 20-year cohort study. Sci Rep. 2020 Feb 26;10(1):3452. doi: 10.1038/s41598-020-60478-5. Read the full text here

Lindberg E, Janson C, Johannessen A, Svanes C, Real FG, Malinovschi A, Franklin KA, Holm M, Schlünssen V, Jogi NO, Gislason T, Benediktsdóttir B. Sleep time and sleep-related symptoms across two generations - results of the community-based RHINE and RHINESSA studies. Sleep Med. 2020 Jan 10;69:8-13. doi:10.1016/j.sleep.2019.12.017. [Epub ahead of print]. Read the full text here

Wang J, Janson C, Lindberg E, Holm M, Gislason T, Benediktsdóttir B, Johannessen A, Schlünssen V, Jogi R, Franklin KA, Norbäck D. Dampness and mold at home and at work and onset of insomnia symptoms, snoring and excessive daytime sleepiness. Environ Int. 2020 Apr 6;139:105691. [Epub ahead of print]. Read the full text here

Peralta GP, Marcon A, Carsin AE, Abramson MJ, Accordini S, Amaral AF, Antó JM, Bowatte G, Burney P, Corsico A, Demoly P, Dharmage S, Forsberg B, Fuertes E, Garcia-Larsen V, Gíslason T, Gullón JA, Heinrich J, Holm M, Jarvis DL, Janson C, Jogi R, Johannessen A, Leynaert B, Rovira JM, Nowak D, Probst-Hensch N, Raherison C, Sánchez-Ramos JL, Sigsgaard T, Siroux V, Squillacioti G, Urrutia I, Weyler J, Zock JP, Garcia-Aymerich J. Body mass index and weight change are associated with adult lung function trajectories: the prospective ECRHS study. Thorax. 2020 Apr;75(4):313-320. doi: 10.1136/thoraxjnl-2019-213880. [Epub ahead of print]. Read the full text here

Janson E, Johannessen A, Holm M, Franklin K, Holst GJ, Gislason T, Jögi R, Lindberg E, Svartengren M, Janson C. Insomnia associated with traffic noise and proximity to traffic-a cross-sectional study of the Respiratory Health in Northern Europe III population. J Clin Sleep Med. 2020 Apr 15;16(4):545-552. Read the full text here

Marcon A, Marchetti P, Antó JM, Cazzoletti L, Cerveri I, Corsico A, Ferreira DS, Garcia-Aymerich J, Gislason D, Heinrich J, Jõgi R, Johannessen A, Leynaert B, Malinovschi A, Pin I, Probst-Hensch N, Weyler J, Janson C, Jarvis D, Accordini S; Ageing Lungs in European Cohorts (ALEC) study. Atopy Modifies the Association Between Inhaled Corticosteroid Use and Lung Function Decline in Patients with Asthma. J Allergy Clin Immunol Pract. 2020 Mar;8(3):980-988.e10. Read the full text here

Mørkve Knudsen GT, Rezwan FI, Johannessen A, Skulstad SM, Bertelsen RJ, Real FG, Krauss-Etschmann S, Patil V, Jarvis D, Arshad SH, Holloway JW, Svanes C. Epigenome-wide association of father's smoking with offspring DNA methylation: a hypothesis-generating study. Environ Epigenet. 2019 Dec 6;5(4) doi:10.1093/eep/dvz023. Erratum in: Environ Epigenet. 2020 Feb 04;6(1). Read the full paper here

Königstein K, Infanger D, Jacobsen Bertelsen R, Johannessen A, Waje- Andreassen U, Schmidt-Trucksäss A, Svanes C, Dratva J. Is atopic sensitization associated with indicators of early vascular ageing in adolescents? PLoS One. 2019 Aug 15;14(8):e0220198. doi: 10.1371/journal.pone.0220198. Read the full text here

Olivieri M, Murgia N, Carsin AE, Heinrich J, Benke G, Bono R, Corsico AG, Demoly P, Forsberg B, Gislason T, Janson C, Jõgi R, Leynaert B, Martínez- Moratalla Rovira J, Norbäck D, Nowak D, Pascual S, Pin I, Probst-Hensch N, Raherison C, Sigsgaard T, Svanes C, Torén K, Urrutia I, Weyler J, Jarvis D, Zock JP, Verlato G. Effects of smoking bans on passive smoking exposure at work and at home. The European Community respiratory health survey. Indoor Air. 2019 Jul;29(4):670-679. doi: 10.1111/ina.12556. [Epub ahead of print]. Read the full text here

Lau MYZ, Dharmage SC, Burgess JA, Win AK, Lowe AJ, Lodge CJ, Perret J, Hui J, Thomas PS, Giles G, Thompson BR, Abramson MJ, Walters EH, Matheson MC; investigators of the TAHS and MACS. Early-life exposure to sibling modifies the relationship between CD14 polymorphisms and allergic sensitization. Clin Exp Allergy. 2019 Mar. Read more here.

Timm S, Schlünssen V, Benediktsdottir B, Bertelsen RJ, Bråbäck L, Holm M, Jogi R, Malinovschi A, Svanes C, Frydenberg M. Offspring reports on parental place of upbringing: Is it valid? Epidemiology. 2019 doi: 10.1097/EDE.0000000000000988. [Epub ahead of print] Read the full text here.

Timm S, Frydenberg M, Abramson MJ, Bertelsen RJ, Bråbäck L, Benediktsdottir B,Gislason T, Holm M, Janson C, Jogi R, Johannessen A, Kim JL, Malinovschi A, Mishra G, Moratalla J, Sigsgaard T, Svanes C, Schlünssen V. Asthma and selective migration from farming environments in a three-generation cohort study. Eur J Epidemiol. 2019 Feb 7. doi: 10.1007/s10654-019-00491-9. [Epub ahead of print]. Read the full text here.

Pape K, Svanes C, Malinovschi A, Benediktsdottir B, Lodge C, Janson C, Moratalla J, Sánchez-Ramos JL, Bråbäck L, Holm M, Jögi R, Bertelsen RJ, Sigsgaard T, Johannessen A, Schlünssen V. Agreement of offspring-reported parental smoking status: the RHINESSA generation study. BMC Public Health. 2019 Jan 21;19(1):94. Read the full text here. 

Triebner K, Accordini S, Calciano L, Johannessen A, Benediktsdóttir B, Bifulco E, Demoly P, Dharmage SC, Franklin KA, Garcia-Aymerich J, Gullón Blanco JA, Heinrich J, Holm M, Jarvis D, Jõgi R, Lindberg E, Martínez-Moratalla J, Muniozguren Agirre N, Pin I, Probst-Hensch N, Raherison C, Sánchez-Ramos JL, Schlünssen V, Svanes C, Hustad S, Leynaert B, Gómez Real F. Exogenous female sex steroids may reduce lung ageing after menopause: A 20-year follow-up study of a general population sample (ECRHS). Maturitas. 2019 Feb;120:29-34. doi:10.1016/j.maturitas.2018.11.007. [Epub ahead of print]. 

Flexeder C, Zock JP, Jarvis D, Verlato G, Olivieri M, Benke G, Abramson MJ, Sigsgaard T, Svanes C, Torén K, Nowak D, Jõgi R, Martinez-Moratalla J, Demoly P, Janson C, Gislason T, Bono R, Holm M, Franklin KA, Garcia-Aymerich J, Siroux V, Leynaert B, Dorado Arenas S, Corsico AG, Pereira-Vega A, Probst-Hensch N, Urrutia Landa I, Schulz H, Heinrich J. Second-hand smoke exposure in adulthood and lower respiratory health during 20 year follow up in the European Community Respiratory Health Survey. Respir Res. 2019 Feb 14;20(1):33. doi: 10.1186/s12931-019-0996-z. Read the full text here

Carsin AE, Fuertes E, Schaffner E, Jarvis D, Antó JM, Heinrich J, Bellisario V, Svanes C, Keidel D, Imboden M, Weyler J, Nowak D, Martinez-Moratalla J, Gullón JA, Sanchez Ramos JL, Caviezel S, Beckmeyer-Borowko A, Raherison C, Pin I, Demoly P, Cerveri I, Accordini S, Gislason T, Toren K, Forsberg B, Janson C, Jogi R, Emtner M, Gómez Real F, Raza W, Leynaert B, Pascual S, Guerra S, Dharmage SC, Probst-Hensch N, Garcia-Aymerich J. Restrictive spirometry pattern is associated with low physical activity levels. A population based international study. Respir Med. 2019 Jan;146:116-123. doi:10.1016/j.rmed.2018.11.017. [Epub ahead of print]. Read the full text here

Bengtsson C, Jonsson L, Holmström M, Hellgren J, Franklin K, Gislason T, Holm M, Johannessen A, Jögi R, Schlünssen V, Janson C, Lindberg E. Incident chronic rhinosinusitis is associated with impaired sleep quality – results of the RHINE study. J Clin Sleep Med. 2019 Jun 15;15(6):899-905. Read the full text here


Nerpin E, Olivieri M, Gislason T, Olin AC, Nielsen R, Johannessen A, Ferreira DS, Marcon A, Cazzoletti L, Accordini S, Pin I, Corsico A, Demoly P, Weyler J, Nowak D, Jõgi R, Forsberg B, Zock JP, Sigsgaard T, Heinric J, Bono R, Leynaert B, Jarvis D, Janson C, Malinovschi A; European Community Respiratory Health Survey (ECRHS) study group. Determinants of fractional exhaled nitric oxide in healthy men and women from the European Community Respiratory Health Survey III. Clin Exp Allergy. 2019 Apr 1. [Epub ahead of print]. Read the full text here

Wang J, Pindus M, Janson C, Sigsgaard T, Kim JL, Holm M, Sommar J, Orru H, Gislason T, Johannessen A, Bertelsen RJ, Norbäck D. Dampness, mould, onset and remission of adult respiratory symptoms, asthma and rhinitis. Eur Respir J. 2019 Mar 17. [Epub ahead of print]. Read the full text here

Janson C, Accordini S, Cazzoletti L, Cerveri I, Chanoine S, Corsico A, Ferreira DS, Garcia-Aymerich J, Gislason D, Nielsen R, Johannessen A, Jogi R, Malinovschi A, Martinez-Moratalla Rovira J, Marcon A, Pin I, Quint J, Siroux V, Almar E, Bellisario V, Franklin KA, Gullón JA, Holm M, Heinrich J, Nowak D, Sánchez-Ramos JL, Weyler JJ, Jarvis D. Pharmacological treatment of asthma in a cohort of adults during a 20-year period: results from the European Community Respiratory Health Survey I, II and III. ERJ Open Res. 2019. Feb 1;5(1). Read the full text here

Emilsson OI, Hägg SA, Lindberg E, Franklin KF, Toren K, Benediktsdottir B, Aspelund T, Gómez Real F, Leynaert B, Demoly P, Sigsgaard T, Perret J, Malinovschi A, Jarvis D, Garcia-Aymerich J, Gislason T,  Janson C. Snoring and nocturnal reflux: Association to lung function decline and respiratory symptoms. ERJ Open Res. 2019. Read the full text here.




Pérez Barrionuevo AM, Gómez Real F, Igland J, Johannessen A, Omenaas E, Franklin KA, Pérez Barrionuevo L, Åstrøm AN, Bertelsen RJ and Svanes C. Periodontal health status and lung function in two Norwegian cohorts. PLoS One. 2018 Jan 19;13(1). Read the full text here.

Kuiper IN, Svanes C, Benediktsdottir B, Bertelsen RJ, Bråbäck L, Dharmage SC, Holm M, Janson C, Jögi R, Malinovschi A, Matheson M, Moratalla JM, Real FG, Sánchez-Ramos JL, Schlünssen V, Timm S, Johannessen A. Agreement in reporting of asthma by parents or offspring - the RHINESSA generation study. BMC Pulm Med. 2018 Jul 27;18(1):122. Read the full text here.

Hammer B, Wagner C, Divac Rankov A, Reuter S, Bartel S, Hylkema MN, Krüger A, Svanes C, Krauss-Etschmann S. In utero exposure to cigarette smoke and effects across generations: A conference of animals on asthma. Clin Exp Allergy. 2018 Nov;48(11):1378-1390. Read the full text here.

 Janson C, Johannessen A, Franklin K, Svanes C, Schiöler L, Malinovschi A, Gislason T, Benediktsdottir B, Schlünssen V, Jõgi R, Jarvis D, Lindberg E. Change in the prevalence asthma, rhinitis and respiratory symptom over a 20 year period: associations to year of birth, life style and sleep related symptoms. BMC Pulm Med. 2018 Sep 12;18(1):152. Read the full text here.

Marcon A, Pesce G, Calciano L, Bellisario V, Dharmage SC, Garcia-Aymerich J, Gislasson T, Heinrich J, Holm M, Janson C, Jarvis D, Leynaert B, Matheson MC, Pirina P, Svanes C, Villani S, Zuberbier T, Minelli C, Accordini S; Ageing Lungs In European Cohorts study. Trends in smoking initiation in Europe over 40 years: A retrospective cohort study. PLoS One. 2018 Aug 22;13(8):e0201881. Read the full text here.

Mørkve Knudsen T, Rezwan FI, Jiang Y, Karmaus W, Svanes C, Holloway JW.Transgenerational and intergenerational epigenetic inheritance in allergic diseases. J Allergy Clin Immunol. 2018 Sep;142(3):765-772. Read the full text here.

Gómez Real F, Burgess JA, Villani S, Dratva J, Heinrich J, Janson C, Jarvis D, Koplin J, Leynaert B, Lodge C, Lærum BN, Matheson MC, Norbäck D, Omenaas ER, Skulstad SM, Sunyer J, Dharmage SC, Svanes C. Maternal age at delivery, lung function and asthma in offspring: a population-based survey. Eur Respir J. 2018 Jun 7;51(6). pii: 1601611. Read the full text here.

Erbas B, Knudsen TM, Janson C, Nilsen RM, Accordini S, Benediktdottir B, Dratva J, Heinrich J, Jarvis D, Leynaert B, Matheson MC, Norbäck D, Real FG, Raherison-Semjen C, Villani S, Dharmage SC, Svanes C. Critical age windows in the impact of lifetime smoking exposure on respiratory symptoms and disease among ever smokers. Environ Res. 2018 Mar 6;164:241-247. Read the full text here.

Accordini S, Calciano L, Johannessen A, Portas L, Benediktsdóttir B, Bertelsen RJ, Bråbäck L, Carsin AE, Dharmage SC, Dratva J, Forsberg B, Gomez Real F, Heinrich J, Holloway JW, Holm M, Janson C, Jögi R, Leynaert B, Malinovschi A, Marcon A, Martínez-Moratalla Rovira J, Raherison C, Sánchez-Ramos JL, Schlünssen V, Bono R, Corsico AG, Demoly P, Dorado Arenas S, Nowak D, Pin I, Weyler J, Jarvis D, Svanes C; Ageing Lungs in European Cohorts (ALEC) Study. A three-generation study on the association of tobacco smoking with asthma. Int J Epidemiol. 2018 Aug 1;47(4):1106-1117. Read the full text here. 

Lønnebotn M, Svanes C, Igland J, Franklin KA, Accordini S, Benediktsdóttir B, Bentouhami H, Blanco JAG, Bono R, Corsico A, Demoly P, Dharmage S, Dorado Arenas S, Garcia J, Heinrich J, Holm M, Janson C, Jarvis D, Leynaert B, Martinez-Moratalla J, Nowak D, Pin I, Raherison-Semjen C, Sánchez-Ramos JL, Schlünssen V, Skulstad SM, Dratva J, Gómez Real F. Body silhouettes as a tool to reflect obesity in the past. PLoS One. 2018 Apr 25;13(4):e0195697. Read the full text here.

Svanes Ø, Bertelsen RJ, Lygre SH, Carsin AE, Antó JM, Forsberg B, García-García JM, Gullón JA, Heinrich J, Holm M, Kogevinas M, Urrutia I, Leynaert B, Moratalla JM, Le Moual N, Lytras T, Norbäck D, Nowak D, Olivieri M, Pin I, Probst-Hensch N, Schlünssen V, Sigsgaard T, Skorge TD, Villani S, Jarvis D, Zock JP, Svanes C. Cleaning at Home and at Work in Relation to Lung Function Decline and Airway Obstruction. Am J Respir Crit Care Med. 2018 May 1;197(9):1157-1163. Read the full text here. 

Jõgi NO and Svanes C, Siiak SP, Logan E, Holloway JW, Igland J, Johannessen A, Levin M, Real FG, Schlunssen V, Horsnell WGC, Bertelsen RJ. Zoonotic helminth exposure and risk of allergic diseases: A study of two generations in Norway. Clin Exp Allergy. 2018 Jan;48(1):66-77. Read the full text here. 

Lønnebotn M, Natvig GK, Benediktsdóttir B, Burgess JA, Holm M, Jogi R, Lindberg E, Macsali F, Schlünssen V, Skulstad SM, Franklin KA, Vanky E, Real FG. “Polycystic ovary syndrome and body mass index as related to hypertensive disorders in pregnancy”. Pregnancy Hypertension.  2018 Jan;11:32-37. Read the full text here.

Fuertes E, Markevych I, Jarvis D, Vienneau D, de Hoogh K, Antó JM, Bowatte G, Bono R, Corsico AG, Emtner M, Gislason T, Gullón JA, Heinrich J, Henderson J, Holm M, Johannessen A, Leynaert B, Marcon A, Marchetti P, Moratalla JM, Pascual S, Probst-Hensch N, Sánchez-Ramos JL, Siroux V, Sommar J, Weyler J, Kuenzli N, Jacquemin B, Garcia-Aymerich J. Residential air pollution does not modify the positive association between physical activity and lung function in current smokers in the ECRHS study. Environ Int. 2018 Aug 16;120:364-372. Read the full text here

Marcon A, Locatelli F, Keidel D, Beckmeyer-Borowko AB, Cerveri I, Dharmage SC, Fuertes E, Garcia-Aymerich J, Heinrich J, Imboden M, Janson C, Johannessen A, Leynaert B, Erquicia SP, Pesce G, Schaffner E, Svanes C, Landa IU, Jarvis D, Probst-Hensch N, Accordini S. Airway responsiveness to metacholine and incidence of COPD: an international prospective cohort study. Thorax 2018, 73(9):825-832. Read the full text here

Mindus S, Malinovschi A, Ekerljung L, Forsberg B, Gíslason T, Jõgi R, Franklin KA, Holm M, Johannessen A, Middelveld R, Schlünssen V, Svanes C, Torén K, Lindberg E, Janson C. Asthma and COPD overlap (ACO) is related to a high burden of sleep disturbance and respiratory symptoms: Results from the RHINE and Swedish GA2LEN surveys. PLoS One. 2018, 13(4):e0195055. Read the full text here

Janson C, Johannessen A, Franklin K, Svanes C, Schiöler L, Malinovschi A, Gislason T, Benediktsdottir B, Schlünssen V, Jögi R, Jarvis D, Lindberg E. Change in the prevalence asthma, rhinitis and respiratory symptoms over a 20 year period: Associations to year of birth, life style and sleep related symptoms. BMC Pulm Med. 2018. 18(1):152. Read the full text here


Skulstad SM, Igland J, Johannessen A, Bertelsen RJ, Lønnebotn M, Omenaas ER, Svanes C and Real FG. Validation of maternal reported pregnancy and birth characteristics against the Medical Birth Registry of Norway. PLoS One. 2017 Aug 4;12(8). Read the full text here.

Svanes C , Koplin J, Skulstad SM, Johannessen A, Bertelsen RJ, Benediktsdottir B, Bråbäck L, Elie Carsin A, Dharmage S, Dratva J, Forsberg B, Gislason T, Heinrich J, Holm M, Janson C, Jarvis D, Jögi R, Krauss-Etschmann S, Lindberg E, Macsali F, Malinovschi A, Modig L, Norbäck D, Omenaas E, Waatevik Saure E, Sigsgaard T, Skorge TD, Svanes Ø, Torén K, Torres C, Schlünssen V, Gomez Real F. Father's environment before conception and asthma risk in his children: a multi-generation analysis of the Respiratory Health In Northern Europe. Int J Epidemiol. 2017 Feb 1;46(1). Read the full text here.


Pereira-Vega A, Sánchez-Ramos JL, Alvarado-Gómez F, Maldonado-Pérez JA, Svanes C , Gómez Real F."Risk factors of Premenstrual Asthma. A systematic review and meta-analysis". Expert Rev Respir Med. 2017 Jan. Read the full text here.


Russell MA, Janson C, Real FG, Johannessen A, Waatevik MJ, Benediktsdóttir B, Holm M, Lindberg E, Schlünssen V, Raza W, Svanes C* and Dharmage S* shared last authorship. “Physical activity and asthma: a longitudinal and multi-country study”. Journal of Asthma. 2017 Feb. Read the full text here.


Dratva D, Zemp E, Dharmage SC, Accordini S, Burdet L, Gislason T, Heinrich J, Janson C, Jaravis D, deMarco R, Norbäck D, Pons M, Real FG, Sunyer J, Villani S, Probst-Hensch N, Svanes C. Early Life Origins of Lung Ageing: Early Life Exposures and Lung Function Decline in Adulthood in Two European Cohorts Aged 28-73 Years. PLoS One. 2016 Jan 26;11(1):e0145127. Read the full text here.


Dratva J, Bertelsen R, Janson C, Johannessen A, Benediktsdottir B, Bråbäck L, Forsberg B, Gislason T, Jarvis D, Jögi R, Lindberg E, Omenaas E, Schlünssen V, Skorge TD, Sigsgaard T, Torén K, Waatevik M, Wielander G, Dharmage SC, Svanes C* and Real FG*. *shared last author. Validation of self-reported figural drawing scales against anthropometric measurements in adults. Public Health Nutr. 2016 Feb 16:1-8. Read the full text here.


Real FG, L. Perez Barrionuevo, K. Franklin, E. Lindberg, R. J. Bertelsen, B. Benediktsdottir, B. Forsberg, T. Gislason, R. Jogi, A. Johannessen, E. Omenaas, E. Saure, V. Schlunssen, T. D. Skorge, K. Toren, A. Perez Saavedra, O. Svanes, A. N. Astrom, C. Janson and C. Svanes (2016). "The Association of Gum Bleeding with Respiratory Health in a Population Based Study from Northern Europe." PLoS One 11(1): e0147518. Read the full text here.

André F. S. Amaral, David P. Strachan, Francisco Gómez Real, Peter G. J. Burney, Deborah L. Jarvis (2016) “Lower lung function associates with cessation of menstruation: UK Biobank data”. Eur Resp J. 2016 Sep 22. pii: ERJ-00412-2016. doi: 10.1183/13993003.00412-2016. Read the full text here.

Campbell B, Raherison C, Lodge C, Lowe A, Gislason T, Heinrich J, Sunyer J, Real FG , Norbäck D, Matheson M , Wjst M, Dratva J, De Marco R, Jarvis D , Janson C, Leynaert B, Svanes C, Dharmage S. “Growing up on a farm as related to adult lung function and allergic phenotypes: An international population based study”. Thorax 2016. Sep 26. Read the full text here.
 

Rovira, Nerea Muniozguren Agirre, Isabelle Pin, Nicole Probst-Hensch, Luca Puggini, Chantal Raherison, José Luis Sánchez-Ramos, Vivi Schlünssen, Jordi Sunyer, Cecilie Svanes, Steinar Hustad, Bénédicte Leynaert* and Francisco Gómez Real. “Menopause is associated with accelerated lung function decline in the longitudinal European Community Respiratory Health Survey”. Am J Resp Med Crit Care. 2016 Dec. Read the full text here.


Aanerud M, Carsin AE, Sunyer J, Dratva J, Gislason T, Jarvis D, deMarco R, Raherison C, Wjst M, Dharmage SC, Svanes C. Interaction between asthma and smoking increases the risk of adult airway obstruction. Eur Respir J. 2015 Mar;45(3):635-43. doi: 10.1183/09031936.00055514. Epub 2014 Nov 27. PubMed PMID: 25431272. Read more here.

Svanes Ø, Skorge TD, Johannessen A, Bertelsen RJ, Bråtveit M, Forsberg B, Gislason T, Holm M, Janson C, Jögi R, Macsali F, Norbäck D, Omenaas ER, Real FG, Schlünssen V, Sigsgaard T, Wieslander G, Zock JP, Aasen T, Dratva J, Svanes C. Respiratory Health in Cleaners in Northern Europe: Is Susceptibility Established in Early Life? PLoS One. 2015 Jul 13. Read more here.


Timm S, Frydenberg M, Janson C, Campbell B, Forsberg B, Gislason T, Holm M, Jogi R, Omenaas E, Sigsgaard T, Svanes C* and Schlünssen V*. *shared last author. The Urban-Rural Gradient In Asthma: A Population-Based Study in Northern Europe. Int J Environ Res Public Health. 2015 Dec 30;13(1). Read more here.


Matheson MC, Burgess JA, Lau MYZ, Lowe AJ, Gurrin LC, Hopper JL, Giles GG, Johns DP, Walters EH, Abramson MJ, Real FG and Dharmage SC (2015). “Hormonal contraception increases risk of asthma among obese women”. ERJ Open Res, 2015. Read more here.



Johannessen A, Verlato G, Benediktsdottir B, Forsberg B, Franklin K, Gislason T, Holm M, Janson C, Jögi R, Lindberg E, Macsali F, Omenaas E, Real FG, Saure EW, Schlünssen V, Sigsgaard T, Skorge TD, Svanes C, Torén K, Waatevik M, Nilsen RM, de Marco R. Longterm follow-up in European respiratory health studies - patterns and implications. BMC Pulm Med. 2014 Apr 16. Read more here.

 
Macsali, F., C. Svanes, R. B. Sothern, B. Benediktsdottir, L. Bjorge, J. Dratva, K. A. Franklin, M. Holm, C. Janson, A. Johannessen, E. Lindberg, E. R. Omenaas, V. Schlunssen, E. Zemp and Real FG (2013). "Menstrual cycle and respiratory symptoms in a general Nordic-Baltic population." Am J Respir Crit Care Med 187(4): 366-373. Read more here


Leynaert, B., J. Sunyer, R. Garcia-Esteban, C. Svanes, D. Jarvis, I. Cerveri, J. Dratva, T. Gislason, J. Heinrich, C. Janson, N. Kuenzli, R. de Marco, E. Omenaas, C. Raherison, Real FG, M. Wjst, E. Zemp, M. Zureik, P. G. Burney, J. M. Anto and F. Neukirch (2012). "Gender differences in prevalence, diagnosis and incidence of allergic and non-allergic asthma: a population-based cohort." Thorax 67(7): 625-631. Read more here


Macsali, F., C. Svanes, L. Bjorge, E. R. Omenaas and Real FG (2012). "Respiratory health in women: from menarche to menopause." Expert Rev Respir Med 6(2): 187-202. Review. Read more here

 


Macsali, F., Real FG, E. Plana, J. Sunyer, J. Anto, J. Dratva, C. Janson, D. Jarvis, E. R. Omenaas, E. Zemp, M. Wjst, B. Leynaert and C. Svanes (2011). "Early age at menarche, lung function, and adult asthma." Am J Respir Crit Care Med 183(1): 8-14. Read more here.

Svanes C, Sunyer J, Plana E, Dharmage S, Heinrich J, Jarvis D, de Marco R, Norbäck D, Raherison C, Villani S, Wjst M, Svanes K, Antó JM. Early life origins of chronic obstructive pulmonary disease. Thorax. 2010 Jan;65(1):14-20. Read more here.


Dratva, J., C. Schindler, I. Curjuric, D. Stolz, F. Macsali, Real FG, E. Zemp and S. Team (2010). "Perimenstrual increase in bronchial hyperreactivity in premenopausal women: results from the population-based SAPALDIA 2 cohort." J Allergy Clin Immunol 125(4): 823-829. Read more here



Abstracts


Three-generation effects of tobacco smoking on lung function within the paternal line. Accordini S et al & Schlünssen V (last author). ERS congress 2017. Link to published abstract

 Oral microbiome and associations with chemical exposure, asthma and lung function. Bertelsen RJ et al & Svanes C (last author). ERS congress 2017. Link to published abstract

 Fathers' overweight and offspring asthma – an intergenerational perspective. Johannessen A et al & Svanes C (last author). Late breaking abstract, ERS congress 2017. Link to published abstract

Epigenome-wide association of father's smoking on offspring DNA methylation. Knudsen TM et al & Svanes C (last author). Late breaking abstract, ERS congress 2017. Link to published abstract

 Validation of self-reported asthma in a generation study. Kuiper IN et al & Johannessen A (last author). ERS congress 2017. Link to published abstract

Mothers' preconception overweight and offspring asthma. Lønnebotn M et al & Svanes and Jarvis (last authors). Late breaking abstract, ERS congress 2017. Link to published a​bstract

Validation of smoking status reported by parents and their offspring –The RHINESSA generation study. Pape K et al & Schlüssen V (last author). ERS congress 2017. Link to published abstract

Use of oral and nasal tobacco and asthma symptoms in a Nordic population. Bertelsen RJ et al & Svanes C (last author). ERS congress 2016. Link to published abstract

Poor periodontal health is associated with airways obstruction. Perez A et al & Svanes C (last author). ERS congress 2016. Link to published abstract

Sist oppdatert 02.08.2023