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MS and research

MS and clinical studies

Multiple sclerosis (MS) is a chronic neurological condition that affects the brain and spinal cord. Symptoms and disease progression can vary considerably from person to person, but advances in research and treatment have transformed the outlook for many people living with MS.

Today, a growing number of highly effective therapies can reduce disease activity, prevent relapses, and help preserve long-term function. For many people living with MS, early diagnosis and treatment make it possible to maintain an active and fulfilling life.

We now believe that MS develops through a complex interaction between genetic, environmental, and immune-related factors. Although many questions remain unanswered, scientific progress over the past decades has greatly improved our understanding of the disease and opened the door to more personalized treatment approaches.

At Neuro-SysMed, we are committed to improving the lives of people with MS through clinical research and innovation. We conduct a range of clinical studies in Bergen and through national and international collaboration, exploring new treatment strategies, diagnostic tools, and biomarkers that may contribute to more precise and effective care.

In addition to disease-modifying therapies, symptom management and rehabilitation play an important role in helping people with MS maintain their independence, well-being, and quality of life.

Our MS research aims to:

  • develop and improve treatment strategies for people living with MS
  • provide people living with MS in Norway with early access to promising new therapies through clinical studies
  • identify biomarkers that can support earlier diagnosis and more accurate disease monitoring
  • advance personalized medicine by tailoring treatment to individual patients
  • improve our understanding of disease progression and treatment response
  • help people with MS achieve the best possible long-term outcomes

Current investigator-initiated clinical trials for MS

Current industry-sponsored clinical trials:

  • A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab in Patients with Multiple Sclerosis (OLERO). Sponsor: Roche.
  • A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants with Multiple Sclerosis. Sponsor: Sanofi.
  • Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS). Sponsor: Sanofi.
  • Non-relapsing Secondary Progressive Multiple Sclerosis (NRSPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (HERCULES). Sponsor: Sanofi.
  • LEMTRADA-PASS Study: A prospective, multicentre, observational, post-authorisation safety study to evaluate the long-term safety profile of LEMTRADA® (alemtuzumab) treatment in patients with relapsing forms of multiple sclerosis. Sponsor: Sanofi.

Completed clinical trials for MS

Last updated 7/7/2026